Ua hoʻomohala ʻia ka nui o nā mea lapaʻau, diagnostic, a me ka noiʻi-oriented nano-scale a me nā molekole e hana i loko o nā cell ola.ʻOiai ʻoi aku ka maikaʻi o ka nui o kēia mau ʻāpana i kā lākou hana, ʻo ia ka paʻakikī o ka hāʻawi ʻana iā lākou ʻo ia ka paʻakikī maoli i ka hoʻohana ʻana iā lākou no nā kumu hana.ʻO ka mea maʻamau, hoʻohana ʻia kekahi ʻano moku no ka lawe ʻana i kēia mau ʻāpana i loko o nā pūnaewele a i ʻole ua haki ka membrane cell e hoʻokuʻu i nā mea hoʻouka kaua. paʻakikī e hoʻokaʻawale.

I kēia manawa, ua hoʻomohala kahi hui o nā hoa hana mai ke Kulanui o Korea a me Okinawa Institute of Science and Technology Graduate University ma Iapana i kahi ala hou loa e kiʻi ai i nā ʻāpana a me nā pūhui kemika, me nā protein, DNA, a me nā lāʻau lapaʻau, i loko o nā cell me ka ʻole o ka pōʻino nui. .

Ke hilinaʻi nei ka ʻenehana hou i ka hoʻokumu ʻana i nā vortex a puni nā cell e hoʻololi i nā membrane cellular no ka manawa lōʻihi e hoʻokuʻu i nā mea i loko.Hana ʻia kēia mau mea a pau i ka ʻanuʻu hoʻokahi a ʻaʻole koi i nā biochemistry paʻakikī, nā kaʻa lawe nano, a i ʻole ka pōʻino mau i nā cell pili.

ʻO ka mea i kūkulu ʻia no ka hana, i kapa ʻia he spiral hydroporator, hiki ke hoʻopuka i nā nanoparticles gula, nā nanoparticles silica mesoporous hana, dextran, a me ka mRNA i loko o nā ʻano ʻāpana like ʻole i loko o hoʻokahi minuke ma kahi kūpono a hiki i 96% a me ke ola cellular a hiki i 94. %.ʻO kēia mau mea a pau ma kahi o hoʻokahi miliona mau kelepona i kēlā me kēia minuke a mai kahi mea maʻalahi e hana a maʻalahi hoʻi e hana.

"Ua pilikia nā ʻano o kēia manawa i nā palena he nui, me nā pilikia me ka scalability, ke kumukūʻai, ka haʻahaʻa haʻahaʻa a me ka cytotoxicity," wahi a Professor Aram Chung mai ke Kula o Biomedical Engineering ma Korea University, ke alakaʻi noiʻi."ʻO kā mākou pahuhopu ka hoʻohana ʻana i nā microfluidics, kahi mākou i hoʻohana ai i ka ʻano o nā kahawai liʻiliʻi o ka wai, e hoʻomohala i kahi hopena hou ikaika no ka hoʻopuka intracellular… nanomaterial - kahe mai nā ʻaoʻao ʻelua.Hoʻokahi minuke wale nō ka hana holoʻokoʻa. "

Aia i loko o ka mea microfluidic nā hui kuʻekuʻe a me nā hui T e kahe ai nā pūnaewele a me nā nanoparticles.Hoʻokumu ka junction configurations i nā vortex e pono ai e alakaʻi i ke komo ʻana o nā membrane cell a komo maoli nā nanoparticles i ka wā e hiki mai ai ka manawa kūpono.

Eia ka hoʻohālikelike o ka vortex spiral e hoʻopōʻino ana i ke kelepona ma ka hui kea a me ka hui T:

Hoʻololi nā ʻenehana lapaʻau i ka honua!E hui pū me mākou a ʻike i ka holomua i ka manawa maoli.Ma Medgadget, hōʻike mākou i nā nūhou ʻenehana hou loa, nīnauele i nā alakaʻi ma ke kula, a waiho i nā hoʻouna mai nā hanana olakino a puni ka honua mai 2004.

Hoʻololi nā ʻenehana lapaʻau i ka honua!E hui pū me mākou a ʻike i ka holomua i ka manawa maoli.Ma Medgadget, hōʻike mākou i nā nūhou ʻenehana hou loa, nīnauele i nā alakaʻi ma ke kula, a waiho i nā hoʻouna mai nā hanana olakino a puni ka honua mai 2004.