Mamiriyoni emhando dzakasiyana dzekurapa, yekuongorora, uye yekutsvagisa-inotungamirwa nano-scale zvishandiso uye mamorekuru akagadzirwa kuti ashande mukati memasero mapenyu.Kunyange zvazvo zvizhinji zvezvikamu izvi zvichinyatsoshanda pane zvavanoita, kazhinji kacho kuoma kwekuzviburitsa ndiro dambudziko chairo mukuzvishandisa pazvinangwa zvinoshanda.Kazhinji, ingave imwe mhando yemidziyo inoshandiswa kutakura zvimedu izvi mumaseru kana kuti cell membrane yatyoka kuti vapambi vapinde. Saka, nzira idzi dzinogona kukuvadza maseru kana kuti hadzina kunaka pakuunza zvinhu zvadzo nguva dzose, uye dzinogona zvakaoma kuita otomatiki.
Iye zvino, chikwata chevashandi vanobva kuKorea University neOkinawa Institute of Science and Technology Graduate University kuJapan vakagadzira nzira itsva yekuwana zvidimbu nemakemikari emakemikari, anosanganisira mapuroteni, DNA, nemishonga, kupinda mukati memasero pasina kukuvadza zvakanyanya. .
Nzira itsva iyi inotsamira pakugadzira maspiral vortexs akatenderedza maseru anombo kanganisa ma cellular membranes akareba zvekuti zvinhu zvipinde mukati. Ma membrane anoita seanobva angozvidzoreredza pazvaaida kana vortex stimulation yapera.Zvese izvi zvinoitwa munhanho imwe uye hazvidi chero yakaoma biochemistry, nano kutakura mota, kana kukuvadzwa zvachose kumaseru anobatanidzwa.
Mudziyo wakavakirwa basa racho, unonzi spiral hydroporator, unogona kuendesa goridhe nanoparticles, functional mesoporous silica nanoparticles, dextran, uye mRNA mumhando dzakasiyana dzemasero mukati meminiti pakubudirira kunosvika 96% uye kurarama kweserura kunosvika makumi mapfumbamwe nemana. %.Zvose izvi pamwero usingadaviriki wemasero angangosvika miriyoni paminiti imwe chete uye kubva pachigadzirwa chakachipa kugadzira uye chiri nyore kushandisa.
"Nzira dzemazuva ano dzinotambura nekukanganisa kwakawanda, kusanganisira nyaya dzine scalability, mutengo, kushanda kwakaderera uye cytotoxicity," akadaro Purofesa Aram Chung kubva kuChikoro cheBiomedical Engineering paKorea University, chidzidzo chinotungamira."Chinangwa chedu chaive chekushandisa microfluidics, kwatakashandisa maitiro emvura diki, kugadzira mhinduro nyowani ine simba yekutakura intracellular ... nanomaterial - inoyerera kubva kune mamwe maviri magumo.Zvose zvinotora miniti imwe chete. "
Iyo yemukati meiyo microfluidic mudziyo ine michinjika michinjika uye T junctions umo maseru uye nanoparticles inoyerera.Iyo junction configurations inogadzira iyo inodiwa vortexes inotungamira kupinda kwesero membranes uye nanoparticles inongopinda mukati kana mukana wamuka.
Heino simulation ye spiral vortex iyo inokonzeresa kushanduka kwesero pamuchinjiko uye T-junction:
Tekinoroji dzekurapa dzinoshandura nyika!Joinha isu uye uone kufambira mberi munguva chaiyo.PaMedgadget, tinoshuma ichangoburwa tekinoroji nhau, kubvunzurudza vatungamiriri vari mumunda, uye faira kutumira kubva kuzviitiko zvekurapa kutenderera pasirese kubvira 2004.
Tekinoroji dzekurapa dzinoshandura nyika!Joinha isu uye uone kufambira mberi munguva chaiyo.PaMedgadget, tinoshuma ichangoburwa tekinoroji nhau, kubvunzurudza vatungamiriri vari mumunda, uye faira kutumira kubva kuzviitiko zvekurapa kutenderera pasirese kubvira 2004.
Nguva yekutumira: Mar-25-2020