Ho entsoe lisebelisoa le limolek'hule tse ngata tse fapaneng tsa kalafo, tlhahlobo, le lipatlisiso tse sebetsang ka har'a lisele tse phelang.Le hoja tse ngata tsa likaroloana tsena li sebetsa haholo ho seo li se etsang, hangata bothata ba ho fana ka tsona ke bona phephetso ea sebele ea ho li sebelisetsa merero e sebetsang.Ka tloaelo, mefuta e meng ea likepe e sebelisoa ho kenya likaroloana tsena liseleng kapa lera la sele le robehile ho lumella bahlaseli ho kena. Ka hona, mekhoa ena e ka lematsa lisele kapa ha e ntle haholo ho fana ka thepa ea bona ka linako tsohle, 'me e ka ho thata ho iketsetsa.

Hona joale, sehlopha sa basebetsi-'moho ho tloha Korea University le Okinawa Institute of Science and Technology Graduate University, Japane, ba thehile mokhoa o sa tloaelehang oa ho fumana likaroloana le metsoako ea lik'hemik'hale, ho akarelletsa le liprotheine, DNA le lithethefatsi, ka hare ho lisele ntle le ho baka tšenyo e khōlō. .

Mokhoa ona o mocha o itšetlehile ka ho etsa li-spiral vortex tse pota-potileng lisele tseo ka nakoana li holofatsang lisele tsa cellular nako e lekaneng hore lintho li kene. Li-membrane tsena li bonahala li khutlela boemong ba tsona hang hang ha ho tsosoa ha vortex ho khaotsa.Sena sohle se etsoa ka mohato o le mong 'me ha se hloke hore ho be le biochemistry e rarahaneng, likoloi tse tsamaisang li-nano, kapa tšenyo e sa feleng ea lisele tse amehang.

Sesebelisoa se etselitsoeng mosebetsi ona, se bitsoang spiral hydroporator, se ka fana ka nanoparticles ea khauta, mesoporous silica nanoparticles, dextran, le mRNA ka mefuta e fapaneng ea lisele ka nako ea motsotso ka katleho e fihlang ho 96% le ho phela ha cellular ho fihla ho 94. %.Sena sohle ka lebelo le makatsang la lisele tse ka bang milione ka motsotso le ho tsoa sesebelisoa se theko e tlaase ho se hlahisa le se bonolo ho se sebetsa.

"Mekhoa ea morao-rao e na le mefokolo e mengata, ho kenyelletsa le mathata a scalability, litšenyehelo, katleho e tlaase le cytotoxicity," ho boletse Moprofesa Aram Chung oa Sekolo sa Biomedical Engineering Univesithing ea Korea, thuto e etellang pele."Sepheo sa rona e ne e le ho sebelisa li-microfluidics, moo re ileng ra sebelisa hampe boits'oaro ba maqhubu a manyane a metsi, ho hlahisa tharollo e ncha e matla bakeng sa phano ea intracellular ... nanomaterial - e phalla ho tsoa lipheletsong tse ling tse peli.Ts'ebetso eohle e nka motsotso o le mong feela. ”

Bokahare ba sesebelisoa sa microfluidic se na le li-cross junctions le T junctions tseo lisele le nanoparticles li phallang ka tsona.Litlhophiso tsa li-junction li etsa li-vortex tse hlokahalang tse lebisang ho kenella ha lisele tsa lisele le li-nanoparticles ka tlhaho li kena ha monyetla o hlaha.

Mona ke papiso ea spiral vortex e bakang deformation ea sele mateanong a mateano le T-junction:

Theknoloji ea bongaka e fetola lefatše!Eba le rona 'me u bone tsoelopele ka nako ea nnete.Ho Medgadget, re tlaleha litaba tsa morao-rao tsa theknoloji, baetapele ba lipuisano tšimong, le lifaeletso tse tsoang liketsahalong tsa bongaka lefatšeng ka bophara ho tloha 2004.

Theknoloji ea bongaka e fetola lefatše!Eba le rona 'me u bone tsoelopele ka nako ea nnete.Ho Medgadget, re tlaleha litaba tsa morao-rao tsa theknoloji, baetapele ba lipuisano tšimong, le lifaeletso tse tsoang liketsahalong tsa bongaka lefatšeng ka bophara ho tloha 2004.