Izigidi ngezigidi zezixhobo ezahlukeneyo zonyango, ukuxilongwa, kunye nophando olujolise kuphando lwe-nano-scale kunye neemolekyuli ziye zaphuhliswa ukuze zisebenze ngaphakathi kweeseli eziphilayo.Ngelixa uninzi lwala masuntswana lusebenza kakhulu koko lukwenzayo, kudla ngokuba bubunzima bokuhambisa olona celomngeni lokuwasebenzisela iinjongo ezibonakalayo.Ngokwesiqhelo, mhlawumbi uhlobo oluthile lwemikhumbi lusetyenziselwa ukuthwala la masuntswana kwiiseli okanye inwebu yeseli yaphukile ukuvumela abahlaseli bangene. Ngokunjalo, obu buchule bungonakalisa iiseli okanye abulunganga kakhulu ekuhambiseni imithwalo yabo rhoqo, kwaye banokuba luncedo. kunzima ukuzenzela.

Ngoku, iqela labadibanisi abavela kwiYunivesithi yaseKorea kunye ne-Okinawa Institute of Science and Technology Graduate University eJapan baye baphuhlisa indlela entsha yokufumana amasuntswana kunye neekhompawundi zekhemikhali, kubandakanya iiproteni, iDNA, kunye neziyobisi, ngaphakathi kweeseli ngaphandle kokwenza umonakalo omkhulu. .

Ubuchwephesha obutsha buxhomekeke ekudaleni i-spiral vortexes ezijikeleze iiseli eziguqula okwexeshana iiseli zeseli ixesha elide ngokwaneleyo ukuba zivumele izinto zingene. Iinwebu zibonakala zibuyela kwimeko yazo yakuqala xa uvuselelo lwevortex luphelile.Konke oku kwenziwa kwinqanaba elinye kwaye ayifuni nayiphi na i-biochemistry enzima, izithuthi zokuhambisa i-nano, okanye umonakalo osisigxina kwiiseli ezibandakanyekayo.

Isixhobo esakhelwe umsebenzi, esibizwa ngokuba yi-spiral hydroporator, sinokuzisa i-nanoparticles yegolide, i-mesoporous silica nanoparticles esebenzayo, i-dextran, kunye ne-mRNA kwiintlobo ezahlukeneyo zeeseli ngaphakathi komzuzu ngokusebenza kakuhle ukuya kuthi ga kwi-96% kunye nokusinda kweselula ukuya kuthi ga kwi-94. %.Konke oku ngesantya esimangalisayo seeseli ezimalunga nesigidi ngomzuzu nakwisixhobo esinexabiso eliphantsi ukusivelisa nekulula ukusisebenza.

"Iindlela zangoku zinengxaki yokulinganiselwa okuninzi, kubandakanywa nemiba enobunzima, iindleko, ukusebenza kakuhle kunye ne-cytotoxicity," watsho uNjingalwazi Aram Chung ovela kwiSikolo soBunjineli beBiomedical kwiYunivesithi yaseKorea, isifundo esikhokelayo."Injongo yethu yayikukusebenzisa i-microfluidics, apho sasixhaphaza ukuziphatha kwamanzi amancinci, ukuphuhlisa isisombululo esitsha esinamandla sokuhanjiswa kwe-intracellular ... Upompa nje ulwelo oluneeseli kunye nama-nanomaterials kwiziphelo ezimbini, kunye neeseli - ngoku ziqulethe I-nanomaterial - ukuphuma kwezinye iziphelo ezimbini.Yonke le nkqubo ithatha umzuzu omnye kuphela. ”

Ingaphakathi lesixhobo se-microfluidic sineendlela ezinqamlezileyo kunye ne-T edibeneyo apho iiseli kunye ne-nanoparticles zihamba.Ulungelelwaniso lwe-junction ludala i-vortexes efunekayo ekhokelela ekungeneni kweembrane zeseli kunye ne-nanoparticles ngokwemvelo ingena xa ithuba livela.

Nalu ufaniso lwe-spiral vortex ebangela ukuguqulwa kweeseli kwindawo enqumlayo kunye ne-T-junction:

Itekhnoloji yezonyango iguqula ihlabathi!Sijoyine kwaye ubone inkqubela ngexesha lokwenyani.Kwi-Medgadget, sixela iindaba zetekhnoloji zamva nje, iinkokeli zodliwano-ndlebe ebaleni, kunye neefayile ezithunyelwa kwiziganeko zonyango kwihlabathi liphela ukusukela ngo-2004.

Itekhnoloji yezonyango iguqula ihlabathi!Sijoyine kwaye ubone inkqubela ngexesha lokwenyani.Kwi-Medgadget, sixela iindaba zetekhnoloji zamva nje, iinkokeli zodliwano-ndlebe ebaleni, kunye neefayile ezithunyelwa kwiziganeko zonyango kwihlabathi liphela ukusukela ngo-2004.